TBX18 and ARC

Data Source:
BioGRID (two hybrid)

		TBX18	ARC
Description		T-box transcription factor 18	activity regulated cytoskeleton associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Repressor Complex	Acrosomal Vesicle Cytoplasm Plasma Membrane Cell Cortex Actin Cytoskeleton Early Endosome Membrane Neuronal Cell Body Dendritic Spine Membrane Raft Neuronal Ribonucleoprotein Granule Postsynaptic Density Membrane Postsynaptic Endosome Glutamatergic Synapse Extracellular Vesicle
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Sequence-specific Double-stranded DNA Binding	MRNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Somitogenesis Sinoatrial Node Development Regulation Of Transcription By RNA Polymerase II Morphogenesis Of Embryonic Epithelium Smooth Muscle Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Sinoatrial Node Cell Fate Commitment Sinoatrial Node Cell Development Ureter Development Cochlea Morphogenesis Regulation Of SA Node Cell Action Potential	Endocytosis Cytoskeleton Organization Endoderm Development Learning Long-term Memory Anterior/posterior Pattern Specification Cell Migration Regulation Of Cell Morphogenesis Regulation Of Neuronal Synaptic Plasticity Modulation Of Chemical Synaptic Transmission MRNA Transport Protein Homooligomerization Long-term Synaptic Potentiation Dendritic Spine Morphogenesis Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Vesicle-mediated Intercellular Transport Regulation Of Long-term Synaptic Potentiation Regulation Of Long-term Synaptic Depression Positive Regulation Of AMPA Receptor Activity
Pathways			NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Diabetic retinopathy in type 2 diabetes ( 25364816) Lung function ( 31902109) Monobrow ( 27182965) Pulse pressure ( 30224653)	Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Automobile speeding propensity ( 30643258)
Interacting Genes		4 interacting genes: ARC KRTAP8-1 PLEKHG4 TRAF1	7 interacting genes: CSRP2 KRT15 S100P SH2D4A SPTBN4 TBX18 UBE3A
Entrez ID		9096	23237
HPRD ID		19076	12469
Ensembl ID		ENSG00000112837	ENSG00000198576
Uniprot IDs		O95935	Q7LC44
PDB IDs
Enriched GO Terms of Interacting Partners?
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