TBX19 and LONRF1

Data Source:
BioGRID (two hybrid)

		TBX19	LONRF1
Description		T-box transcription factor 19	LON peptidase N-terminal domain and ring finger 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Metal Ion Binding
	Biological Process	Mesoderm Formation Cell Fate Specification Somitogenesis Heart Morphogenesis Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Pituitary Gland Development Regulation Of Cell Population Proliferation Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Protein Polyubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Adrenocorticotropic hormone deficiency; Isolated ACDH deficiency (IAD)
GWAS			Apolipoprotein A1 levels ( 32203549) Colorectal cancer (diet interaction) ( 24743840) HDL cholesterol levels ( 32203549)
Interacting Genes		15 interacting genes: GCM2 HGS HOXC8 IRX6 LONRF1 NEDD9 NR5A1 PITX1 POGZ PRR35 RAB2B TBX6 TFG VENTX ZIC1	96 interacting genes: ADAMTSL4 ALAS1 AP2B1 ATG9A AVPI1 BHLHB9 BRCA1 BYSL C4orf17 CALCOCO2 CBLL2 CDKN2D CFP CRX CYSRT1 DVL3 EFHC2 FLACC1 GABPB2 GORASP1 GORASP2 HLX HOXA1 HSPB1 IHO1 IKZF2 IKZF3 IQCF2 KAT5 KATNBL1 KCTD21 KCTD9 KHDC1 KRT31 KRT35 KRT75 KRTAP1-3 KRTAP13-1 KRTAP13-3 KRTAP19-6 KRTAP19-7 KRTAP3-3 KRTAP6-1 LGALS9B LHX2 LHX4 LNX1 MAGED1 MGAT5B MID2 MRPL38 MTMR3 MYOZ3 NR4A1 NTAQ1 OOEP PATZ1 PAX5 PAX6 PAX8 PICK1 PLSCR1 POU6F2 PPP1R3C PRDM16 PRDM6 PRR35 PSMA1 RBPMS RIMBP3C RPRD1A SFN SLU7 SPRY2 STAU1 STX11 TASOR2 TBX19 TRAF2 TRIM27 TRIM42 TRIM8 TRIM9 UBE2I UBE2L6 UCHL3 USP2 VGLL1 WDR83 XIAP YPEL3 ZFP90 ZNF426 ZNF653 ZNF774 ZNHIT2
Entrez ID		9095	91694
HPRD ID		05214	08674
Ensembl ID		ENSG00000143178	ENSG00000154359
Uniprot IDs		B3KRD9 O60806	Q17RB8
PDB IDs
Enriched GO Terms of Interacting Partners?
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