UNC119 and PPP3CC

Data Source:
BioGRID (two hybrid)

		UNC119	PPP3CC
Description		unc-119 lipid binding chaperone	protein phosphatase 3 catalytic subunit gamma
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Intercellular Bridge Synapse Spindle Midzone	Cytoplasm Mitochondrion Cytosol Calcineurin Complex Presynapse Glutamatergic Synapse
	Molecular Function	Protein Binding Lipid Binding	Protein Binding Calmodulin Binding Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis	Protein Dephosphorylation Brain Development Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Activation of BAD and translocation to mitochondria DARPP-32 events
Drugs
Diseases
GWAS			General risk tolerance (MTAG) ( 30643258) HIV-1 viral setpoint ( 20205591) Verbal declarative memory ( 25648963)
Interacting Genes		103 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A KRTAP1-3 KRTAP9-3 KRTAP9-8 LAMA4 LCK LIG4 LRIF1 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PPP3CA PPP3CC PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RBPMS2 RCAN3 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TMEM200A TP53BP2 TP53I3 TP53INP1 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24	14 interacting genes: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B HAX1 ITPKC PPP3R1 SDC2 SPATA33 TGFBR1 THAP7 UNC119
Entrez ID		9094	5533
HPRD ID		04927	00236
Ensembl ID		ENSG00000109103	ENSG00000120910
Uniprot IDs		K7EN86 Q13432	P48454
PDB IDs		3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A
Enriched GO Terms of Interacting Partners?
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