PPP3CC and ITPKC

Data Source:
BioGRID (two hybrid)

		PPP3CC	ITPKC
Description		protein phosphatase 3 catalytic subunit gamma	inositol-trisphosphate 3-kinase C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Calcineurin Complex Presynapse Glutamatergic Synapse	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Protein Binding Calmodulin Binding Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Inositol Hexakisphosphate Kinase Activity Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Kinase Activity
	Biological Process	Protein Dephosphorylation Brain Development Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Inositol Phosphate Biosynthetic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation
Pathways		Activation of BAD and translocation to mitochondria DARPP-32 events	Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) HIV-1 viral setpoint ( 20205591) Verbal declarative memory ( 25648963)	Blood protein levels ( 28240269) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Kawasaki disease ( 33106546 22081228)
Interacting Genes		14 interacting genes: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B HAX1 ITPKC PPP3R1 SDC2 SPATA33 TGFBR1 THAP7 UNC119	1 interacting genes: PPP3CC
Entrez ID		5533	80271
HPRD ID		00236	09400
Ensembl ID		ENSG00000120910	ENSG00000086544
Uniprot IDs		P48454	A0A024R0N8 Q96DU7
PDB IDs			2A98
Enriched GO Terms of Interacting Partners?
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