PKMYT1 and STEAP3

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		PKMYT1	STEAP3
Description		protein kinase, membrane associated tyrosine/threonine 1	STEAP3 metalloreductase
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane	Cytoplasm Endosome Multivesicular Body Plasma Membrane Endosome Membrane Integral Component Of Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Cupric Reductase Activity Metal Ion Binding Ferric-chelate Reductase (NADPH) Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Phosphorylation Regulation Of Mitotic Nuclear Division Negative Regulation Of Phosphatase Activity Meiotic Cell Cycle	Apoptotic Process Cell Cycle Protein Secretion Copper Ion Import Transferrin Transport Regulation Of Apoptotic Process Iron Ion Homeostasis
Pathways		Polo-like kinase mediated events Cyclin A/B1/B2 associated events during G2/M transition Cyclin A/B1/B2 associated events during G2/M transition G2/M DNA replication checkpoint	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Transferrin endocytosis and recycling
Drugs		Fostamatinib
Diseases
GWAS		Metabolic syndrome ( 20694148)	Cocaine dependence ( 23958962) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Renal cell carcinoma x sex interaction ( 31231134)
Interacting Genes		24 interacting genes: ABHD16A BCL2 CCNB1 CD3E CD79A CDK1 CLDN8 ELOVL4 FATE1 LIME1 LRRC25 MAPK10 MAPK8 MFSD14B MFSD5 PIN1 PLK1 RETREG3 SLC10A1 SLC30A8 STEAP3 TMEM101 TMEM229B TMX2	6 interacting genes: BAD BNIP3L MTDH PKMYT1 SETD7 TPT1
Entrez ID		9088	55240
HPRD ID		03920	10285
Ensembl ID		ENSG00000127564	ENSG00000115107
Uniprot IDs		Q0IJ49 Q99640	A1P3F0 B8ZZX6 Q658P3
PDB IDs		3P1A 5VCV 5VCW 5VCX 5VCY 5VCZ 5VD0 5VD1 5VD3	2VNS 2VQ3
Enriched GO Terms of Interacting Partners?
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