ARTN and LDB1

Data Source:
BioGRID (proximity labelling technology)

		ARTN	LDB1
Description		artemin	LIM domain binding 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cell Leading Edge Protein-containing Complex Beta-catenin-TCF Complex
	Molecular Function	Signaling Receptor Binding Protein Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding	RNA Polymerase II Activating Transcription Factor Binding DNA Binding Chromatin Binding Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association DNA-binding Transcription Factor Binding
	Biological Process	MAPK Cascade Signal Transduction Neuroblast Proliferation Axon Guidance Peripheral Nervous System Development Induction Of Positive Chemotaxis Peyer's Patch Morphogenesis Lymphocyte Migration Into Lymphoid Organs	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Nervous System Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of Cell Migration Regulation Of Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Mesendoderm Development Regulation Of Focal Adhesion Assembly Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		NCAM1 interactions RAF/MAP kinase cascade RET signaling	RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Tea consumption ( 31046077)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494) Pulse pressure ( 30578418)
Interacting Genes		1 interacting genes: GFRA3	32 interacting genes: ATXN1 CTDSP1 DNMT3L ESR1 IDI2 IRAK3 ISL1 ISL2 LHX1 LHX2 LHX3 LHX4 LHX6 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP
Entrez ID		9048	8861
HPRD ID		04863	09144
Ensembl ID		ENSG00000117407	ENSG00000198728
Uniprot IDs		Q5T4W7	A0A6E1WJ75 Q86U70
PDB IDs		2ASK 2GH0 2GYR 2GYZ 6Q2S	2XJY 2XJZ 2YPA 6TYD
Enriched GO Terms of Interacting Partners?
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