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LDB1 and SSBP4
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
LDB1
SSBP4
Description
LIM domain binding 1
single stranded DNA binding protein 4
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cell Leading Edge
Protein-containing Complex
Beta-catenin-TCF Complex
Nucleus
Molecular Function
RNA Polymerase II Activating Transcription Factor Binding
DNA Binding
Chromatin Binding
Transcription Coregulator Activity
Protein Binding
Enzyme Binding
LIM Domain Binding
Protein Homodimerization Activity
Protein Self-association
DNA-binding Transcription Factor Binding
Single-stranded DNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery
Gastrulation With Mouth Forming Second
Hair Follicle Development
Regulation Of Transcription, DNA-templated
Transcription By RNA Polymerase II
Multicellular Organism Development
Nervous System Development
Anterior/posterior Axis Specification
Epithelial Structure Maintenance
Wnt Signaling Pathway
Cerebellar Purkinje Cell Differentiation
Cellular Component Assembly
Neuron Differentiation
Regulation Of Cell Migration
Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Somatic Stem Cell Population Maintenance
Regulation Of Kinase Activity
Histone H3-K4 Acetylation
Negative Regulation Of Erythrocyte Differentiation
Positive Regulation Of Cell Adhesion
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Hemoglobin Biosynthetic Process
Mesendoderm Development
Regulation Of Focal Adhesion Assembly
Regulation Of Hematopoietic Stem Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS
General cognitive ability (
29844566
)
Intelligence (MTAG) (
29326435
)
Mean reticulocyte volume (
32888494
)
Pulse pressure (
30578418
)
Alzheimer's disease (late onset) (
30820047
)
Basophil count (
32888494
)
Breast cancer (
23535729
)
Intake of total sugars (
31005972
)
Monocyte count (
27863252
)
Systemic lupus erythematosus (
33536424
28714469
)
Interacting Genes
32 interacting genes:
ATXN1
CTDSP1
DNMT3L
ESR1
IDI2
IRAK3
ISL1
ISL2
LHX1
LHX2
LHX3
LHX4
LHX6
LHX8
LHX9
LMO1
LMO2
LMO3
LMO4
LMX1A
LMX1B
LSM7
POLR1B
PSMA1
PSMD10
RLIM
SP1
SSBP1
SSBP2
SSBP3
SSBP4
TOLLIP
8 interacting genes:
IL36RN
LDB1
LDB2
MYO15B
PIK3R3
PIN1
SPG21
TFAP2B
Entrez ID
8861
170463
HPRD ID
09144
09579
Ensembl ID
ENSG00000198728
ENSG00000130511
Uniprot IDs
A0A6E1WJ75
Q86U70
Q9BWG4
PDB IDs
2XJY
2XJZ
2YPA
6TYD
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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