LDB1 and SSBP1

Data Source:
HPRD (in vitro)

		LDB1	SSBP1
Description		LIM domain binding 1	single stranded DNA binding protein 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cell Leading Edge Protein-containing Complex Beta-catenin-TCF Complex	Nucleus Mitochondrion Mitochondrial Matrix Nucleoid Mitochondrial Nucleoid Extracellular Exosome
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding DNA Binding Chromatin Binding Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association DNA-binding Transcription Factor Binding	Chromatin Binding Single-stranded DNA Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Nervous System Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of Cell Migration Regulation Of Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Mesendoderm Development Regulation Of Focal Adhesion Assembly Regulation Of Hematopoietic Stem Cell Differentiation	Mitochondrial DNA Replication DNA Unwinding Involved In DNA Replication Mitochondrion Organization Positive Regulation Of Helicase Activity Mitochondrion Morphogenesis Positive Regulation Of DNA Helicase Activity
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs	Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494) Pulse pressure ( 30578418)	Anorexia nervosa ( 23568457)
Interacting Genes		32 interacting genes: ATXN1 CTDSP1 DNMT3L ESR1 IDI2 IRAK3 ISL1 ISL2 LHX1 LHX2 LHX3 LHX4 LHX6 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP	10 interacting genes: CDK1 CKS1B CKS2 GCM2 LDB1 LGALS7 LGALS7B OTUD6A POLG YWHAQ
Entrez ID		8861	6742
HPRD ID		09144	02703
Ensembl ID		ENSG00000198728	ENSG00000106028
Uniprot IDs		A0A6E1WJ75 Q86U70	A4D1U3 B7Z268 Q04837
PDB IDs		2XJY 2XJZ 2YPA 6TYD	1S3O 2DUD 3ULL
Enriched GO Terms of Interacting Partners?
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