OTULIN and SUSD6

Data Source:
BioGRID (two hybrid)

		OTULIN	SUSD6
Description		OTU deubiquitinase with linear linkage specificity	sushi domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol LUBAC Complex	Cellular_component Integral Component Of Membrane
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity	Molecular_function Protein Binding
	Biological Process	Sprouting Angiogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Wnt Signaling Pathway Protein Ubiquitination Protein Phosphopantetheinylation Negative Regulation Of NF-kappaB Transcription Factor Activity Innate Immune Response Negative Regulation Of Inflammatory Response Regulation Of Canonical Wnt Signaling Pathway Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Protein Linear Deubiquitination	Cellular Response To DNA Damage Stimulus Cell Death
Pathways		Regulation of TNFR1 signaling Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Asthma (childhood onset) ( 31036433) Cerebrospinal fluid neurofilament light levels ( 31930058)
Interacting Genes		11 interacting genes: BCL10 DAZAP2 DVL2 FAM168A OTUD7B SFT2D1 SPART SPATA2 SUSD6 TMEM239 UBE2D1	9 interacting genes: ADAMTSL4 DCUN1D1 FAM241B KRTAP1-3 KRTAP10-8 MTURN OTULIN TMEM19 UBXN6
Entrez ID		90268	9766
HPRD ID		14266	10010
Ensembl ID		ENSG00000154124	ENSG00000100647
Uniprot IDs		Q96BN8	Q92537
PDB IDs		3ZNV 3ZNX 3ZNZ 4KSJ 4KSK 4KSL 4OYK 4P0B 5OE7 6I9C 6SAK
Enriched GO Terms of Interacting Partners?
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