CLIC3 and DNM1

Data Source:
HPRD (in vitro)

		CLIC3	DNM1
Description		chloride intracellular channel 3	dynamin 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Body Chloride Channel Complex Extracellular Exosome	Nucleoplasm Cytoplasm Microtubule Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Mitochondrial Membrane Dendritic Spine Head Extracellular Exosome Presynapse Postsynaptic Endocytic Zone Membrane
	Molecular Function	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding	RNA Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	Glutathione Metabolic Process Chloride Transport Signal Transduction Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Endocytosis Receptor-mediated Endocytosis Endosome Organization Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Ephrin Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization
Pathways			Toll Like Receptor 4 (TLR4) Cascade Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057) Body mass index ( 26426971) Coenzyme Q10 levels ( 27149984) Platelet distribution width ( 32888494)
Interacting Genes		35 interacting genes: AGR2 ALX1 ANKRD23 ANKRD55 APP C7orf31 C9orf24 DDIT4L DNM1 EFHC2 FAM166B GLYR1 INCA1 KATNBL1 KRT85 KRTAP13-3 LELP1 MAPK15 MBD3L1 MECOM MIA3 MSX2 POT1 PROSER2 SCML4 STMN3 TBC1D3 TBC1D3C TBC1D3K TEPSIN TLE5 VPS4A ZBTB42 ZC2HC1C ZNF620	46 interacting genes: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CEP126 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GRB2 GRIN1 GRIN2D ITSN1 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP RACK1 SH3GL1 SH3GL2 SH3GL3 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I
Entrez ID		9022	1759
HPRD ID		05941	03851
Ensembl ID		ENSG00000169583	ENSG00000106976
Uniprot IDs		O95833 Q6FGP1	B4DK06 B7ZAC0 Q05193
PDB IDs		3FY7 3KJY	1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS 4UUD 4UUK 5D3Q 6DLU 6DLV 6S9A
Enriched GO Terms of Interacting Partners?
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