DNM1 and TIMM50

Data Source:
HPRD (two hybrid)

		DNM1	TIMM50
Description		dynamin 1	translocase of inner mitochondrial membrane 50
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Mitochondrial Membrane Dendritic Spine Head Extracellular Exosome Presynapse Postsynaptic Endocytic Zone Membrane	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Integral Component Of Membrane Nuclear Speck
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding	RNA Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Interleukin-2 Receptor Binding Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Endocytosis Receptor-mediated Endocytosis Endosome Organization Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Ephrin Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization	Release Of Cytochrome C From Mitochondria Protein Dephosphorylation Mitochondrial Membrane Organization Protein Import Into Mitochondrial Matrix Peptidyl-tyrosine Dephosphorylation
Pathways		Toll Like Receptor 4 (TLR4) Cascade Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Clathrin-mediated endocytosis	Mitochondrial protein import
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Body mass index ( 26426971) Coenzyme Q10 levels ( 27149984) Platelet distribution width ( 32888494)
Interacting Genes		46 interacting genes: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CEP126 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GRB2 GRIN1 GRIN2D ITSN1 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP RACK1 SH3GL1 SH3GL2 SH3GL3 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I	5 interacting genes: DNM1 LY6E-DT PAFAH1B2 RAF1 TNFRSF10B
Entrez ID		1759	92609
HPRD ID		03851	12118
Ensembl ID		ENSG00000106976	ENSG00000105197
Uniprot IDs		B4DK06 B7ZAC0 Q05193	A0A024R0M6 Q3ZCQ8
PDB IDs		1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS 4UUD 4UUK 5D3Q 6DLU 6DLV 6S9A
Enriched GO Terms of Interacting Partners?
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