NOL3 and VASP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOL3	VASP
Description		nucleolar protein 3	vasodilator stimulated phosphoprotein
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GO Annotations	Cellular Component	Nucleolus Mitochondrion Cytosol Membrane Sarcoplasmic Reticulum	Cytosol Plasma Membrane Bicellular Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Exosome
	Molecular Function	RNA Binding Death Receptor Binding Calcium Ion Binding Protein Binding Death Effector Domain Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Caspase Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Cadherin Binding
	Biological Process	Response To Hypoxia Blood Vessel Remodeling Response To Ischemia MRNA Splice Site Selection RNA Splicing Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Muscle Atrophy Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Response To Injury Involved In Regulation Of Muscle Adaptation Negative Regulation Of Apoptotic Process Protein Complex Oligomerization Negative Regulation Of Necrotic Cell Death Negative Regulation Of Release Of Cytochrome C From Mitochondria Intrinsic Apoptotic Signaling Pathway Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly Protein Homotetramerization
Pathways			Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions
Drugs
Diseases
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
Interacting Genes		16 interacting genes: BAX CASP2 CASP8 CSNK2A1 ETNK2 FADD NIF3L1 POT1 SIRPA SRSF9 TERF1 TERF2IP TFPT TINF2 UBQLN2 VASP	44 interacting genes: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP CDC42 CEP43 DMRTB1 DNMBP ENAH ERMAP EVL FAT1 FRS3 FYB1 GSN IQGAP1 LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A PSORS1C2 RAD51 RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM15 TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX
Entrez ID		8996	7408
HPRD ID		05572	03415
Ensembl ID		ENSG00000140939	ENSG00000125753
Uniprot IDs		O60936 Q5TZN6	A0A024R0V4 P50552
PDB IDs		4UZ0	1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW
Enriched GO Terms of Interacting Partners?
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