NOL3 and ETNK2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOL3	ETNK2
Description		nucleolar protein 3	ethanolamine kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Mitochondrion Cytosol Membrane Sarcoplasmic Reticulum	Cellular_component Cytosol
	Molecular Function	RNA Binding Death Receptor Binding Calcium Ion Binding Protein Binding Death Effector Domain Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Caspase Binding	Ethanolamine Kinase Activity Protein Binding ATP Binding
	Biological Process	Response To Hypoxia Blood Vessel Remodeling Response To Ischemia MRNA Splice Site Selection RNA Splicing Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Muscle Atrophy Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Response To Injury Involved In Regulation Of Muscle Adaptation Negative Regulation Of Apoptotic Process Protein Complex Oligomerization Negative Regulation Of Necrotic Cell Death Negative Regulation Of Release Of Cytochrome C From Mitochondria Intrinsic Apoptotic Signaling Pathway Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	In Utero Embryonic Development Placenta Development Phosphatidylethanolamine Biosynthetic Process Biological_process Post-embryonic Development Phosphorylation Multicellular Organism Growth
Pathways			Synthesis of PE
Drugs
Diseases
GWAS			Periodontitis (CDC/AAP) ( 24024966) Response to acetaminophen (hepatotoxicity) ( 21177773) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		16 interacting genes: BAX CASP2 CASP8 CSNK2A1 ETNK2 FADD NIF3L1 POT1 SIRPA SRSF9 TERF1 TERF2IP TFPT TINF2 UBQLN2 VASP	8 interacting genes: ATN1 CYSRT1 HNRNPK KRTAP12-2 MDFI MID2 NOL3 STX1A
Entrez ID		8996	55224
HPRD ID		05572	13283
Ensembl ID		ENSG00000140939	ENSG00000143845
Uniprot IDs		O60936 Q5TZN6	A0A024R976 A0A024R9A8 B7Z1G7 Q9NVF9
PDB IDs		4UZ0
Enriched GO Terms of Interacting Partners?
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