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PER2 and PER3
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
PER2
PER3
Description
period circadian regulator 2
period circadian regulator 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Perinuclear Region Of Cytoplasm
Nucleus
Cytoplasm
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Transcription Corepressor Binding
Transcription Coactivator Activity
Protein Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Transcription Corepressor Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Response To Ischemia
Glycogen Biosynthetic Process
Gluconeogenesis
Fatty Acid Metabolic Process
Circadian Rhythm
Regulation Of Vasoconstriction
Lactate Biosynthetic Process
Negative Regulation Of Protein Ubiquitination
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Negative Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Regulation Of Neurogenesis
Regulation Of Insulin Secretion
White Fat Cell Differentiation
Regulation Of Cell Cycle
Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse
Negative Regulation Of Fat Cell Proliferation
Histone H3 Deacetylation
Circadian Regulation Of Translation
Positive Regulation Of Cold-induced Thermogenesis
Negative Regulation Of Transcription Regulatory Region DNA Binding
Negative Regulation Of Transcription By RNA Polymerase II
Circadian Regulation Of Gene Expression
Entrainment Of Circadian Clock By Photoperiod
Regulation Of Circadian Sleep/wake Cycle, Sleep
Protein Stabilization
Pathways
Circadian Clock
Drugs
Diseases
Familial advanced sleep phase syndrome
GWAS
Chronotype (
26955885
30696823
27494321
)
Morning vs. evening chronotype (
26955885
26835600
27494321
)
Chronotype (
30696823
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Morning person (
30696823
)
Morning vs. evening chronotype (
26835600
)
Ulcerative colitis (
28067908
)
Interacting Genes
25 interacting genes:
BHLHE41
BTRC
CLOCK
CRY1
CRY2
CSNK1D
CSNK1E
CSNK2B
DELEC1
ELOA
LENG8
LMO4
MDM2
MLH1
PER1
PER3
RORC
TIMELESS
TP53
TPT1
TPTEP2-CSNK1E
UBE2D1
UBE2D2
UBE2D3
UBL4A
9 interacting genes:
ARNTL
CLOCK
CRY1
CRY2
CSNK1D
CSNK1E
PER1
PER2
SP1
Entrez ID
8864
8863
HPRD ID
04575
09138
Ensembl ID
ENSG00000132326
ENSG00000049246
Uniprot IDs
O15055
A0A087WV69
A2I2N5
P56645
PDB IDs
6OF7
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
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