EDF1 and NRL

Data Source:
BioGRID (pull down)

		EDF1	NRL
Description		endothelial differentiation related factor 1	neural retina leucine zipper
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	TFIID-class Transcription Factor Complex Binding DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Calmodulin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Leucine Zipper Domain Binding Sequence-specific Double-stranded DNA Binding Promoter-specific Chromatin Binding
	Biological Process	Regulation Of Transcription, DNA-templated Multicellular Organism Development Regulation Of Lipid Metabolic Process Positive Regulation Of DNA Binding Endothelial Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Visual Perception Positive Regulation Of Transcription By RNA Polymerase II Retinal Rod Cell Development Response To Stimulus
Pathways
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS			Attention deficit hyperactivity disorder symptom score ( 27663945) Liver fibrosis and steatohepatitis severity (MRI cT1 measure) ( 32247823) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		22 interacting genes: ATF1 ATF2 CALM1 CALM2 CALM3 CDC42 CEBPA CREB1 JUN MAPK6 MEOX2 NR1H3 NR5A1 NR5A2 NRL PPARG PRKCA RXRA SOX4 TAF1 TBP UBE2I	6 interacting genes: CRX EDF1 FIZ1 MAPK1 MAPK14 NR2E3
Entrez ID		8721	4901
HPRD ID		09235	08875
Ensembl ID		ENSG00000107223	ENSG00000129535
Uniprot IDs		O60869	P54845
PDB IDs		1X57 6ZVH
Enriched GO Terms of Interacting Partners?
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