KRT37 and CLCNKA

Data Source:
BioGRID (two hybrid)

		KRT37	CLCNKA
Description		keratin 37	chloride voltage-gated channel Ka
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex
	Molecular Function	Structural Molecule Activity Protein Binding	Voltage-gated Chloride Channel Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Keratinization Cornification	Chloride Transport Excretion Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Keratinization Formation of the cornified envelope	Stimuli-sensing channels
Drugs			Niflumic acid Talniflumate
Diseases			Bartter syndrome
GWAS		Squamous cell lung carcinoma ( 28604730)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left ventricular ejection fraction ( 32382064) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		41 interacting genes: AGXT AQP1 BCAS2 BFSP2 C21orf58 CCDC196 CLCNKA COL8A1 DES FAM110A FBXW5 GNG13 HAPLN2 HGS HOXA1 HSF4 KRT1 KRT3 KRT4 KRT6B KRT6C KRT71 KRT74 KRT75 KRT76 KRT81 KRT83 KRT85 KRT86 MTG1 NUFIP2 OIP5 OTX1 PIN1 PKN1 PSMA1 SMARCD1 SMARCE1 TBC1D21 TXLNB USHBP1	22 interacting genes: C7orf31 CYSRT1 IKZF3 KLHL20 KPRP KRT31 KRT34 KRT37 KRT39 KRTAP21-2 KRTAP4-12 KRTAP6-3 LHX3 MBD3L1 PBX4 SLITRK5 SRPK2 TCF12 TCF4 TEPSIN TRIB3 ZNF511
Entrez ID		8688	1187
HPRD ID		05175	03608
Ensembl ID		ENSG00000108417	ENSG00000186510
Uniprot IDs		O76014	P51800
PDB IDs			2PFI
Enriched GO Terms of Interacting Partners?
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