STX16 and STX6

Data Source:
HPRD (in vivo)

		STX16	STX6
Description		syntaxin 16	syntaxin 6
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Focal Adhesion Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane SNARE Complex Golgi Cisterna Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Retrograde Transport, Endosome To Golgi Vesicle Docking Golgi Ribbon Formation	Intracellular Protein Transport Vesicle Fusion Endosome Organization Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases		Pseudohypoparathyroidism
GWAS		Cardiovascular risk factors (age interaction) ( 20838585) Hemoglobin ( 32888494)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Creutzfeldt-Jakob disease (sporadic) ( 32949544) Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: MEOX2 NAPB PTPN12 RHOU SNAP29 STX1A STX2 STX4 STX6 VAMP3 VAMP4 VAMP5 VPS45 VTI1A	35 interacting genes: AQP6 ARMC8 DNAJC5 EBP EEA1 FAM210B GOLM2 GOPC LIME1 LMNA MARCHF2 MEOX2 MMGT1 MTERF2 MTIF3 NAPB PSMA3 PTPN9 SCN3B SNAP23 SNAP29 STOM STX16 STX1A STX2 STX4 STX7 TIMMDC1 TMEM14B TMEM205 TMEM86B TMEM9 VAMP4 VPS11 VPS18
Entrez ID		8675	10228
HPRD ID		04718	07231
Ensembl ID		ENSG00000124222	ENSG00000135823
Uniprot IDs		B4DJX9 O14662	O43752
PDB IDs			2NPS 4J2C
Enriched GO Terms of Interacting Partners?
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