CDK13 and TRIM7

Data Source:
BioGRID (two hybrid)

		CDK13	TRIM7
Description		cyclin dependent kinase 13	tripartite motif containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Cyclin K-CDK13 Complex Extracellular Region Extracellular Space Nucleus Nucleoplasm Golgi Apparatus Cytosol Cyclin/CDK Positive Transcription Elongation Factor Complex Nuclear Speck Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Golgi Apparatus
	Molecular Function	RNA Binding Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Protein Kinase Binding Cyclin Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Transcription Elongation From RNA Polymerase II Promoter Protein Phosphorylation Regulation Of Mitotic Nuclear Division Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Viral Process Hemopoiesis Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Neutrophil Degranulation Phosphorylation Of RNA Polymerase II C-terminal Domain Negative Regulation Of Stem Cell Differentiation	Protein Ubiquitination
Pathways		TP53 Regulates Transcription of DNA Repair Genes Neutrophil degranulation
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Plateletcrit ( 32888494) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		4 interacting genes: CHMP4A PRPF40A SRPK2 TRIM7	27 interacting genes: AQP1 BCAM CDK13 CFL2 CRYGC CTNNAL1 DES GTF2A2 GYG1 IRAK4 MAD2L2 NAA35 NABP1 OTUD6A RAB2A RIN1 RNASE1 RSPH14 RWDD2B SIAH1 SRC TP53I13 TRMT10A UBE2D1 UBE2D2 UBE2D3 UBE2E1
Entrez ID		8621	81786
HPRD ID		04496	11648
Ensembl ID		ENSG00000065883	ENSG00000146054
Uniprot IDs		A0A024RA66 A0A024RA85 Q14004 Q9BVE2	Q9C029
PDB IDs		5EFQ
Enriched GO Terms of Interacting Partners?
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