CASK and IL15RA

Data Source:
BioGRID (two hybrid)

		CASK	IL15RA
Description		calcium/calmodulin dependent serine protein kinase	interleukin 15 receptor subunit alpha
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GO Annotations	Cellular Component	Basement Membrane Nuclear Lamina Nucleolus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Actin Cytoskeleton Nuclear Matrix Presynaptic Membrane Ciliary Membrane	Golgi Membrane Extracellular Space Endosome Endoplasmic Reticulum Membrane Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Vesicle Membrane Nuclear Membrane
	Molecular Function	Guanylate Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding Calmodulin Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Cytokine Receptor Activity Protein Binding Protein Kinase Binding Interleukin-15 Receptor Activity
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Protein Phosphorylation Cell Adhesion Neurotransmitter Secretion Negative Regulation Of Keratinocyte Proliferation GMP Metabolic Process GDP Metabolic Process Negative Regulation Of Wound Healing Negative Regulation Of Cellular Response To Growth Factor Stimulus	Interleukin-15-mediated Signaling Pathway Positive Regulation Of Phagocytosis
Pathways		Dopamine Neurotransmitter Release Cycle Syndecan interactions Nephrin family interactions Neurexins and neuroligins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors	Interleukin-15 signaling Interleukin-15 signaling
Drugs		Formic acid Fostamatinib
Diseases		FG syndrome (FGS); Opitz-Kaveggia syndrome
GWAS			Alopecia areata ( 25608926) Asthma ( 31959851 31619474) Asthma (bronchodilator response) ( 23508266) Atopic dermatitis ( 26482879) Blood protein levels ( 30072576 29875488 28240269) Diisocyanate-induced asthma ( 25918132) Inflammatory bowel disease ( 23128233) Medication use (thyroid preparations) ( 31015401) Neuroblastoma (pediatric) ( 32599975) Soluble interleukin-2 receptor subunit alpha ( 26293465)
Interacting Genes		88 interacting genes: AKAP9 APBA1 ATP2B4 BNIP3L C20orf85 CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DDX54 DLG1 DLG4 DNAJC5 DUSP3 ELL2 EPB41 EPS8 ERBIN F11R FCHSD2 FMR1 GCNT3 GLS2 GRIK2 GRIN2A GTSE1 HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 KIF2A KLC4 LIN7A LIN7B MAPRE1 MAPRE2 MARK2 MARS1 MED1 MLLT6 MLX NDEL1 NPHS1 NRXN1 NRXN2 NRXN3 NTN4 P2RX7 PARD3B PARD6G PCBP2 PCM1 PKP2 PLK2 PPP4R3A PRC1 PRKCI PRKD2 PRKN PRPF3 PTGS2 RAB3A RBBP6 RBM10 RBM14 RBM5 RPA2 RPH3A SDC1 SDC2 SDC3 SDC4 SF3B2 SH2D4A SLAIN2 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WHRN WNT7B YWHAE	12 interacting genes: AXL BCL10 CASK CDK2 CDK4 IL15 IL2RB IL2RG PIAS4 RCVRN SYK TRAF2
Entrez ID		8573	3601
HPRD ID		02164	03045
Ensembl ID		ENSG00000147044	ENSG00000134470
Uniprot IDs		A0A2R8Y6F8 A0A2R8YE77 O14936	A0A0A0MS77 G8CVM3 Q13261
PDB IDs		1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC 6KMH	2ERS 2Z3Q 2Z3R 4GS7
Enriched GO Terms of Interacting Partners?
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