AP3B1 and ARR3

Data Source:
HPRD (in vitro, in vivo)

		AP3B1	ARR3
Description		adaptor related protein complex 3 subunit beta 1	arrestin 3
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Synapse
	Molecular Function	Protein Binding Protein Phosphatase Binding GTP-dependent Protein Binding	G Protein-coupled Receptor Binding Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	Cell Morphogenesis Toll-like Receptor Signaling Pathway Hematopoietic Progenitor Cell Differentiation Respiratory System Process Cellular Protein Modification Process Protein Targeting To Lysosome Cellular Zinc Ion Homeostasis Intracellular Protein Transport Inflammatory Response Lysosome Organization Spermatogenesis Single Fertilization Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Granulocyte Differentiation Melanosome Organization Protein Localization To Cell Surface MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Regulation Of Catalytic Activity Positive Regulation Of NK T Cell Differentiation Platelet Dense Granule Organization Lung Morphogenesis Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Skin Epidermis Development	Regulation Of Protein Phosphorylation G Protein-coupled Receptor Internalization Signal Transduction Visual Perception
Pathways		Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF fusions
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) FEV1 ( 30804560) Insulin resistance/response ( 21901158) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Red cell distribution width ( 32888494) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)
Interacting Genes		14 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 GKAP1 SLC30A3	20 interacting genes: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 DVL2 FSHR GNMT MAP2K7 MARCHF8 OPN1MW OPN4 PLK4 PTAFR RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		8546	407
HPRD ID		04551	02358
Ensembl ID		ENSG00000132842	ENSG00000120500
Uniprot IDs		A0A0S2Z5J4 O00203	P36575
PDB IDs			1XEH 2A34
Enriched GO Terms of Interacting Partners?
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