AP3B1 and AP3S2

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		AP3B1	AP3S2
Description		adaptor related protein complex 3 subunit beta 1	adaptor related protein complex 3 subunit sigma 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm	Golgi Apparatus AP-3 Adaptor Complex Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Axon Cytoplasm
	Molecular Function	Protein Binding Protein Phosphatase Binding GTP-dependent Protein Binding
	Biological Process	Cell Morphogenesis Toll-like Receptor Signaling Pathway Hematopoietic Progenitor Cell Differentiation Respiratory System Process Cellular Protein Modification Process Protein Targeting To Lysosome Cellular Zinc Ion Homeostasis Intracellular Protein Transport Inflammatory Response Lysosome Organization Spermatogenesis Single Fertilization Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Granulocyte Differentiation Melanosome Organization Protein Localization To Cell Surface MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Regulation Of Catalytic Activity Positive Regulation Of NK T Cell Differentiation Platelet Dense Granule Organization Lung Morphogenesis Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Skin Epidermis Development	Intracellular Protein Transport Anterograde Axonal Transport Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF fusions
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) FEV1 ( 30804560) Insulin resistance/response ( 21901158) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Red cell distribution width ( 32888494) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)	Type 2 diabetes ( 24509480 30054458 21874001 29358691 30297969 23945395 32499647 30718926 28869590)
Interacting Genes		14 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 GKAP1 SLC30A3	7 interacting genes: AP3B1 AP3D1 AP3S1 ARF1 ARF6 E2F4 SCARB2
Entrez ID		8546	10239
HPRD ID		04551	03880
Ensembl ID		ENSG00000132842	ENSG00000157823
Uniprot IDs		A0A0S2Z5J4 O00203	A0A024RC62 P59780
PDB IDs
Enriched GO Terms of Interacting Partners?
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