GAS7 and MYBPC2

Data Source:
BioGRID (two hybrid)

		GAS7	MYBPC2
Description		growth arrest specific 7	myosin binding protein C2
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane	Cytosol Myosin Filament
	Molecular Function	Protein Binding Actin Filament Binding	Actin Binding Protein Binding Structural Constituent Of Muscle
	Biological Process	Actin Filament Polymerization Neuron Projection Morphogenesis	Cell Adhesion Muscle Filament Sliding
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Glaucoma ( 30104761 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935) Gut microbiota relative abundance (Prevotella) ( 33208821) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 25173106 24002674 22570627 31798171 29785010 31959993 30054594 28073927 29235454) Medication use (antiglaucoma preparations and miotics) ( 31015401) Proteinuria and chronic kidney disease ( 26420894)	Primary biliary cholangitis ( 26394269)
Interacting Genes		26 interacting genes: ABI1 ACTA1 APBB1IP ATXN1L CDC37 CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH KHDRBS1 LSM4 MCRS1 MYBPC2 NCKAP1 NCKAP1L NCKIPSD NTAQ1 PACSIN1 RPLP0 SF1 SF3A1 SFPQ WASF2 YIF1A	31 interacting genes: ACTN2 AMOT AOC3 CCT6A CMYA5 COL12A1 DST DYSF FLNB FLNC FSD2 GABARAP GAS7 HSPA1B ITGB5 MAD2L2 MSN MYBPC1 MYBPH MYH8 MYOM2 NF2 PCDH12 PDE4DIP RANBP2 SDCBP SGCG TRIM63 TRIP11 TTN TULP3
Entrez ID		8522	4606
HPRD ID		16011	01184
Ensembl ID		ENSG00000007237	ENSG00000086967
Uniprot IDs		O60861	A0A140VJQ0 Q14324
PDB IDs		2LX7 2YSH	2E7C 2EDK 2EDN
Enriched GO Terms of Interacting Partners?
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