MYBPC2 and MAD2L2

Data Source:
BioGRID (two hybrid)

		MYBPC2	MAD2L2
Description		myosin binding protein C2	mitotic arrest deficient 2 like 2
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GO Annotations	Cellular Component	Cytosol Myosin Filament	Nucleus Nucleoplasm Anaphase-promoting Complex Chromosome Nucleolus Spindle Cytosol Zeta DNA Polymerase Complex Site Of Double-strand Break
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle	RNA Polymerase II Activating Transcription Factor Binding Protein Binding JUN Kinase Binding
	Biological Process	Cell Adhesion Muscle Filament Sliding	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Double-strand Break Repair Actin Filament Organization Mitotic Spindle Assembly Checkpoint Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription By Competitive Promoter Binding Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Protein Catabolic Process Error-prone Translesion Synthesis DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Isotype Switching Positive Regulation Of Transcription, DNA-templated Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		Striated Muscle Contraction	Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI
Drugs
Diseases
GWAS		Primary biliary cholangitis ( 26394269)	Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		31 interacting genes: ACTN2 AMOT AOC3 CCT6A CMYA5 COL12A1 DST DYSF FLNB FLNC FSD2 GABARAP GAS7 HSPA1B ITGB5 MAD2L2 MSN MYBPC1 MYBPH MYH8 MYOM2 NF2 PCDH12 PDE4DIP RANBP2 SDCBP SGCG TRIM63 TRIP11 TTN TULP3	47 interacting genes: ADAM15 ADAM17 ADAM9 C20orf85 CAMK2B CDC20 CDH1 DEPDC5 ELK1 FAM217B FTO FZR1 GSC2 IKZF1 IKZF3 INCA1 KCTD9 KRT34 MAD2L1 MAD2L1BP MBD3L1 MYBPC2 PLAGL2 POLDIP2 PPM1B PRCC PRR5L PRRC2A RAB11FIP4 RBBP6 REL REV1 REV3L SFI1 SHLD1 TCF4 THAP6 TRIM27 TRIM54 TRIM7 YPEL3 YY1AP1 ZBED1 ZMYND12 ZNF511 ZNF558 ZNF655
Entrez ID		4606	10459
HPRD ID		01184	07246
Ensembl ID		ENSG00000086967	ENSG00000116670
Uniprot IDs		A0A140VJQ0 Q14324	A0A024R4I4 Q9UI95
PDB IDs		2E7C 2EDK 2EDN	3ABD 3ABE 3VU7 4EXT 4GK0 4GK5 5XPT 5XPU 6BC8 6BCD 6BI7 6K07 6K08 6KEA 6KTO 6NIF
Enriched GO Terms of Interacting Partners?
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