TMEM60 and AMIGO1

Data Source:
BioGRID (two hybrid)

		TMEM60	AMIGO1
Description		transmembrane protein 60	adhesion molecule with Ig like domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Voltage-gated Potassium Channel Complex Integral Component Of Membrane Dendrite Neuronal Cell Body Membrane Perikaryon Pericellular Basket
	Molecular Function	Protein Binding	Protein Binding Potassium Channel Regulator Activity
	Biological Process		Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Voltage-gated Potassium Channel Activity Cellular Response To L-glutamate
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549)
Interacting Genes		89 interacting genes: AMIGO1 ANKS6 APOL2 AQP2 AQP6 ASGR2 BEST2 BIK BSND CD300A CD53 CD74 CLDN7 CNR2 CPLX4 CYB5R3 EBP EDA ERGIC3 EVI2B FAM209A FFAR2 FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPR42 GPX8 HERPUD2 HIBADH HSD17B13 IFNGR2 KCNK5 KIAA2013 LEUTX LHFPL5 LMNA LRRC3B LRRC59 MFF MGST3 MMD MMGT1 PAGE1 PGRMC2 PI16 REEP2 REEP4 RETREG3 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC13A4 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC30A4 SLC35E3 SLC38A1 SLC39A2 SLC4A1 SLC7A8 SPAG4 SPNS3 SSMEM1 STOM STX1A SYT1 THAP4 TLCD4 TMCO5A TMED9 TMEM139 TMEM14B TMEM203 TMEM237 TMEM45B TMEM52B TMEM86B TMEM9 TMPPE TMPRSS2 TTYH1 VMA21	35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2
Entrez ID		85025	57463
HPRD ID		12923	11129
Ensembl ID		ENSG00000135211	ENSG00000181754
Uniprot IDs		Q9H2L4	Q86WK6
PDB IDs
Enriched GO Terms of Interacting Partners?
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