AMIGO1 and PROM2

Data Source:
BioGRID (two hybrid)

		AMIGO1	PROM2
Description		adhesion molecule with Ig like domain 1	prominin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Voltage-gated Potassium Channel Complex Integral Component Of Membrane Dendrite Neuronal Cell Body Membrane Perikaryon Pericellular Basket	Integral Component Of Plasma Membrane Microvillus Cilium Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Microvillus Membrane Cell Projection Microspike Membrane Raft Ciliary Membrane Extracellular Exosome Prominosome
	Molecular Function	Protein Binding Potassium Channel Regulator Activity	Protein Binding Cholesterol Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Voltage-gated Potassium Channel Activity Cellular Response To L-glutamate	Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cell Projection Organization Regulation Of GTPase Activity Negative Regulation Of Pinocytosis Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549)
Interacting Genes		35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2	2 interacting genes: AMIGO1 GPR152
Entrez ID		57463	150696
HPRD ID		11129	17912
Ensembl ID		ENSG00000181754	ENSG00000155066
Uniprot IDs		Q86WK6	B2R879 Q8N271
PDB IDs
Enriched GO Terms of Interacting Partners?
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