ALG10 and KCNH1

Data Source:
HPRD (in vitro)

		ALG10	KCNH1
Description		ALG10 alpha-1,2-glucosyltransferase	potassium voltage-gated channel subfamily H member 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nuclear Inner Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Axon Dendrite Early Endosome Membrane Presynaptic Membrane Perikaryon Intracellular Membrane-bounded Organelle Postsynaptic Density Membrane
	Molecular Function	Protein Binding Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Cyclic Nucleotide Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process	Potassium Ion Transport Myoblast Fusion Regulation Of Ion Transmembrane Transport Regulation Of Cell Population Proliferation Regulation Of Membrane Potential Phosphatidylinositol-mediated Signaling Cellular Response To Calcium Ion Potassium Ion Transmembrane Transport
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Voltage gated Potassium channels
Drugs			Enflurane Imipramine Astemizole Promethazine Miconazole
Diseases
GWAS		Chronotype ( 30696823) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Methadone dose in opioid dependence ( 28115739) Morning person ( 30696823) Triglyceride levels ( 32203549)	Blond vs. brown/black hair color ( 30531825) Bone mineral density (femoral neck) ( 27424934) Bone mineral density (spine) and age at menarche ( 26312577) Bone mineral density (total hip) ( 27424934) Cancer ( 27197191) Cholesterol ( 31902109) Circulating vasoactive peptide levels ( 23381795) Cobalt levels ( 26025379) Hematocrit ( 32888494) Hemoglobin ( 32888494)
Interacting Genes		8 interacting genes: CD79A ERGIC3 FBLN1 HERPUD2 KCNH1 KCNH2 SERP2 SHISAL1	10 interacting genes: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 MTDH NTAQ1 SDCBP
Entrez ID		84920	3756
HPRD ID		10346	04492
Ensembl ID		ENSG00000139133	ENSG00000143473
Uniprot IDs		Q5BKT4	O95259
PDB IDs			5J7E
Enriched GO Terms of Interacting Partners?
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