KCNH1 and KCNF1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCNH1	KCNF1
Description		potassium voltage-gated channel subfamily H member 1	potassium voltage-gated channel modifier subfamily F member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Inner Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Axon Dendrite Early Endosome Membrane Presynaptic Membrane Perikaryon Intracellular Membrane-bounded Organelle Postsynaptic Density Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Cyclic Nucleotide Binding Phosphatidylinositol Bisphosphate Binding	Voltage-gated Potassium Channel Activity Potassium Channel Activity Protein Binding
	Biological Process	Potassium Ion Transport Myoblast Fusion Regulation Of Ion Transmembrane Transport Regulation Of Cell Population Proliferation Regulation Of Membrane Potential Phosphatidylinositol-mediated Signaling Cellular Response To Calcium Ion Potassium Ion Transmembrane Transport	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Imipramine Astemizole Promethazine Miconazole	Enflurane Promethazine Miconazole
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Bone mineral density (femoral neck) ( 27424934) Bone mineral density (spine) and age at menarche ( 26312577) Bone mineral density (total hip) ( 27424934) Cancer ( 27197191) Cholesterol ( 31902109) Circulating vasoactive peptide levels ( 23381795) Cobalt levels ( 26025379) Hematocrit ( 32888494) Hemoglobin ( 32888494)
Interacting Genes		10 interacting genes: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 MTDH NTAQ1 SDCBP	13 interacting genes: ALOX15B CLPTM1L FARS2 KCNG3 KCNG4 KCNH1 KCNV2 MCL1 OPRM1 SERP1 SLC39A7 TCEA2 TSPO
Entrez ID		3756	3754
HPRD ID		04492	04808
Ensembl ID		ENSG00000143473	ENSG00000162975
Uniprot IDs		O95259	Q9H3M0
PDB IDs		5J7E
Enriched GO Terms of Interacting Partners?
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