LINGO1 and FBXW7

LINGO1

FBXW7

Description leucine rich repeat and Ig domain containing 1 F-box and WD repeat domain containing 7
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Essential tremor ( 19182806)
  • Feeling miserable ( 29500382)
  • General factor of neuroticism ( 30867560)
  • Hemoglobin A1c levels ( 29403010)
  • Household income (MTAG) ( 31844048)
  • Intelligence (MTAG) ( 29326435)
  • Neuroticism ( 27089181)
  • Risky sexual behaviors (alcohol dependence interaction) ( 28990359)
  • Systemic lupus erythematosus ( 33536424)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
Interacting Genes 17 interacting genes: EFEMP2 FBLN1 FBXW7 FRS3 GOLGA2 HSD3B7 KRTAP10-1 KRTAP4-12 KRTAP5-6 KRTAP5-9 KRTAP9-2 MACO1 NGFR NTM RTN4R SPAG5 TRIM27 77 interacting genes: AHSG AKT1 ANGPTL4 ANP32B ARL6IP1 BCAS3 BEX1 BLM CCDC6 CCNE1 CCNE2 CDC34 CEBPD CUL1 DISC1 DVL1 EBNA1BP2 EXT1 EZH2 FANCC FBP1 FBP2 GALNT12 GATA2 GATA3 GFI1 GLMN HEMGN HEY1 HIPK2 HNRNPK HRAS IGFBP3 IL24 JUN KLF10 KLF5 LINGO1 MAP2K1 MAPK3 MMS22L MYB MYC MYCN NANS NOTCH1 NOTCH4 NPM1 PLK1 PPARGC1A PPP3R2 PRKN PSEN1 PTPN11 RACK1 RFLNA SCGB3A1 SEC61B SHC1 SHPRH SKP1 SMAD1 SOX9 SREBF1 STAT3 STAT5A STOML1 STYX SUMF2 TGFB1 TMOD1 TP53 TSC22D4 USP9X WDR97 XPA ZNF510
Entrez ID 84894 55294
HPRD ID 14322 05888
Ensembl ID ENSG00000169783 ENSG00000109670
Uniprot IDs Q96FE5 G0Z2K0 Q969H0 S4R3U4
PDB IDs 2ID5 4OQT 2OVP 2OVQ 2OVR 5IBK 5V4B
Enriched GO Terms of Interacting Partners?
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