ZC3H10 and DAB1

Data Source:
BioGRID (two hybrid)

		ZC3H10	DAB1
Description		zinc finger CCCH-type containing 10	DAB adaptor protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cytoplasm Cytosol Brush Border Postsynaptic Density Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Apical Part Of Cell Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding MiRNA Binding Metal Ion Binding	Protein Binding Phosphatidylinositol 3-kinase Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA	Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Axon Guidance Midgut Development Adult Walking Behavior Dendrite Development Ventral Spinal Cord Development Cerebellum Structural Organization Hippocampus Development Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Radial Glia Guided Migration Of Purkinje Cell Response To Drug Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Kinase Activity Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Axonogenesis Golgi Localization Lateral Motor Column Neuron Migration
Pathways			Reelin signalling pathway
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Alzheimer's disease progression score ( 29860282) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Bulimia nervosa ( 23568457) Cardiac troponin-I levels ( 31014085) Coronary artery disease ( 29472232) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Household income (MTAG) ( 31844048) Immune reponse to smallpox (secreted IL-10) ( 22610502) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Kawasaki disease ( 21221998) Lateral orbital frontal cortex volume ( 31530798) Logical memory (delayed recall) in normal cognition ( 29274321) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457) Pubertal anthropometrics ( 23449627) Risk-taking tendency (4-domain principal component model) ( 30643258) Serum linoleic acid concentration in metabolic syndrome ( 31991592) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference ( 28552196) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		46 interacting genes: AOC1 APPBP2 ARID5A ATXN1 BOLL C10orf55 C19orf54 CRX DAB1 DAZAP2 FAM168B FOSB FOXH1 HIVEP1 INTS11 KLHDC7B KRTAP19-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MIR143 MSX2 NCS1 NFYA OTX2 OXER1 PIAS2 PICALM PLA2G10 POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E RBM38 RBPMS RBPMS2 RNF4 STAM2 TENT5A TENT5B TEX37 UBE2I ZNF34	76 interacting genes: APLP1 APLP2 APP ARID5A BHLHE40 C1orf94 CDK5 CIART CLASRP CRK CRKL DAB2IP DAZAP2 ERBB2 ERBB3 FAM168A HMBOX1 HNRNPLL HYAL3 INPP5D ITGB2 ITGB3 ITGB5 ITGB7 ITSN1 KRTAP19-5 KRTAP19-7 KRTAP8-1 LDLR LGALS9B LGALS9C LNX1 LRP1 LRP2 LRP8 MAGED1 MAPK14 MBNL1 MBNL3 MYO6 NAF1 NTAQ1 PAFAH1B1 PCDH18 PIN1 PLCG1 POGZ PPIG PRR20A PTPN11 RAMAC RBFOX1 RBFOX2 RELN RHOXF2 ROR2 SERF2 SIAH1 SIRPB1 SMAP2 SNRPB SOCS6 SOCS7 SRC STRBP TCEA2 TCEANC TMTC3 TOLLIP USP53 VENTX VLDLR ZBTB32 ZC3H10 ZCCHC10 ZNF488
Entrez ID		84872	1600
HPRD ID		07860	04582
Ensembl ID		ENSG00000135482	ENSG00000173406
Uniprot IDs		Q96K80	O75553
PDB IDs
Enriched GO Terms of Interacting Partners?
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