DAB1 and CRKL

  • Data Source:
  • HPRD (in vitro)

DAB1

CRKL

Description DAB adaptor protein 1 CRK like proto-oncogene, adaptor protein
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Alzheimer's disease progression score ( 29860282)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Bulimia nervosa ( 23568457)
  • Cardiac troponin-I levels ( 31014085)
  • Coronary artery disease ( 29472232)
  • Cortical surface area (min-P) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (min-P) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Household income (MTAG) ( 31844048)
  • Immune reponse to smallpox (secreted IL-10) ( 22610502)
  • Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566)
  • Insomnia symptoms (never/rarely vs. usually) ( 30804566)
  • Kawasaki disease ( 21221998)
  • Lateral orbital frontal cortex volume ( 31530798)
  • Logical memory (delayed recall) in normal cognition ( 29274321)
  • Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457)
  • Pubertal anthropometrics ( 23449627)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Serum linoleic acid concentration in metabolic syndrome ( 31991592)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Waist circumference ( 28552196)
  • White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes 76 interacting genes: APLP1 APLP2 APP ARID5A BHLHE40 C1orf94 CDK5 CIART CLASRP CRK CRKL DAB2IP DAZAP2 ERBB2 ERBB3 FAM168A HMBOX1 HNRNPLL HYAL3 INPP5D ITGB2 ITGB3 ITGB5 ITGB7 ITSN1 KRTAP19-5 KRTAP19-7 KRTAP8-1 LDLR LGALS9B LGALS9C LNX1 LRP1 LRP2 LRP8 MAGED1 MAPK14 MBNL1 MBNL3 MYO6 NAF1 NTAQ1 PAFAH1B1 PCDH18 PIN1 PLCG1 POGZ PPIG PRR20A PTPN11 RAMAC RBFOX1 RBFOX2 RELN RHOXF2 ROR2 SERF2 SIAH1 SIRPB1 SMAP2 SNRPB SOCS6 SOCS7 SRC STRBP TCEA2 TCEANC TMTC3 TOLLIP USP53 VENTX VLDLR ZBTB32 ZC3H10 ZCCHC10 ZNF488 79 interacting genes: ABL1 AOX1 AREL1 ARHGAP32 BCAR1 BCR BIK BLK BLNK CBL CBLB CD34 CRK DAB1 DOCK2 DOK1 DOK2 EPHB6 EPOR ERBB2 ERBB3 ETV6 EVL FCGR1A GAB1 GAB2 GAREM1 GRB2 GRN IFNAR1 IGF1R INPP5D INSR IRS4 ITGB1 KHDRBS1 KIDINS220 KIT LAMA5 LTBP4 LYN MAP4K1 MAP4K5 MEGF6 MSL1 NEDD9 NOTCH2 PDGFRA PHC2 PIK3R1 PIK3R2 PLEKHA1 PLSCR1 POLR1D PPFIBP2 PSMC6 PTPDC1 PTPN11 PXN RAPGEF1 RIN3 RPL31 SASH1 SHANK3 SHC1 SOS1 SOS2 STAT5A STAT5B SYK TGFB1I1 TMEM168 TYK2 USP53 WAC WAS WIPF1 YES1 YY1
Entrez ID 1600 1399
HPRD ID 04582 03596
Ensembl ID ENSG00000173406 ENSG00000099942
Uniprot IDs O75553 P46109
PDB IDs 2BZX 2BZY 2DBK 2EO3 2LQN 2LQW
Enriched GO Terms of Interacting Partners?
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