DOC2B and UNC13B

Data Source:
HPRD (two hybrid, in vivo)

		DOC2B	UNC13B
Description		double C2 domain beta	unc-13 homolog B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane SNARE Complex Presynapse	Golgi Apparatus Cytosol Plasma Membrane Membrane Synaptic Vesicle Membrane Neuromuscular Junction Presynaptic Membrane Terminal Bouton Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component
	Molecular Function	Calcium Ion Binding Calcium-dependent Phospholipid Binding	Calcium Ion Binding Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Diacylglycerol Binding GTP-dependent Protein Binding Small GTPase Binding
	Biological Process	Protein Localization Positive Regulation Of Vesicle Fusion Positive Regulation Of Insulin Secretion Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter	Chemical Synaptic Transmission Neurotransmitter Secretion Neuromuscular Junction Development Positive Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Maturation Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Protein Secretion Acrosomal Vesicle Exocytosis Dense Core Granule Priming Cellular Response To Glucose Stimulus Positive Regulation Of Inhibitory Postsynaptic Potential Neuronal Dense Core Vesicle Exocytosis Presynaptic Dense Core Vesicle Exocytosis
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS			Parkinson's disease ( 21812969)
Interacting Genes		3 interacting genes: DYNLT1 STXBP1 UNC13B	11 interacting genes: CLK1 DOC2A DOC2B PDCL2 RIMS1 RPH3AL SPTBN2 STX1A STX1B STX2 TOE1
Entrez ID		8447	10497
HPRD ID		05196	05785
Ensembl ID		ENSG00000272636	ENSG00000198722
Uniprot IDs		Q14184	O14795 Q4LE73
PDB IDs
Enriched GO Terms of Interacting Partners?
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