UNC13B and DOC2B

Data Source:
HPRD (two hybrid, in vivo)

		UNC13B	DOC2B
Description		unc-13 homolog B	double C2 domain beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Plasma Membrane Membrane Synaptic Vesicle Membrane Neuromuscular Junction Presynaptic Membrane Terminal Bouton Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component	Cytoplasm Plasma Membrane SNARE Complex Presynapse
	Molecular Function	Calcium Ion Binding Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Diacylglycerol Binding GTP-dependent Protein Binding Small GTPase Binding	Calcium Ion Binding Calcium-dependent Phospholipid Binding
	Biological Process	Chemical Synaptic Transmission Neurotransmitter Secretion Neuromuscular Junction Development Positive Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Maturation Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Protein Secretion Acrosomal Vesicle Exocytosis Dense Core Granule Priming Cellular Response To Glucose Stimulus Positive Regulation Of Inhibitory Postsynaptic Potential Neuronal Dense Core Vesicle Exocytosis Presynaptic Dense Core Vesicle Exocytosis	Protein Localization Positive Regulation Of Vesicle Fusion Positive Regulation Of Insulin Secretion Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Parkinson's disease ( 21812969)
Interacting Genes		11 interacting genes: CLK1 DOC2A DOC2B PDCL2 RIMS1 RPH3AL SPTBN2 STX1A STX1B STX2 TOE1	3 interacting genes: DYNLT1 STXBP1 UNC13B
Entrez ID		10497	8447
HPRD ID		05785	05196
Ensembl ID		ENSG00000198722	ENSG00000272636
Uniprot IDs		O14795 Q4LE73	Q14184
PDB IDs
Enriched GO Terms of Interacting Partners?
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