RECK and CTIF

Data Source:
BioGRID (two hybrid)

		RECK	CTIF
Description		reversion inducing cysteine rich protein with kazal motifs	cap binding complex dependent translation initiation factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Anchored Component Of Membrane Wnt Signalosome	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Wnt-protein Binding Coreceptor Activity Involved In Canonical Wnt Signaling Pathway	RNA Binding Protein Binding Translation Activator Activity
	Biological Process	Blood Vessel Maturation Sprouting Angiogenesis Embryo Implantation Extracellular Matrix Organization Negative Regulation Of Cell Migration Embryonic Forelimb Morphogenesis Regulation Of Angiogenesis Canonical Wnt Signaling Pathway Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Metalloendopeptidase Activity	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Translational Initiation Positive Regulation Of Translation
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172) IgG glycosylation ( 23382691)	Automobile speeding propensity ( 30643258) Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Iris heterochromicity ( 30895295) Large HDL particle concentration ( 29084231) Lumbar spine bone mineral density (integral) ( 27476799) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231) Red blood cell count ( 32888494 27863252) Response to carboplatin in ovarian cancer (MTT IC50) ( 27047539) Rheumatoid arthritis ( 30891314) White blood cell count ( 32888494)
Interacting Genes		42 interacting genes: ADAM12 BMF C22orf39 CCN3 CEP44 CFP CTH CTIF CYSRT1 DISC1 EFHC2 GLRX3 INCA1 KEAP1 KLHL20 KRT40 KRTAP10-8 KRTAP13-2 KRTAP26-1 KRTAP3-1 LCN1 MEOX2 MLPH MMP9 MTNR1B NBPF19 NDUFB7 NOTCH2NLA NR4A3 NUDT16L1 OXER1 PRIM2 REL SPSB2 SSC4D TCF4 TEKT4 TRIM39 TRIM69 USHBP1 ZNF438 ZNF704	8 interacting genes: ATPAF2 ATXN7L2 DDX19A HEXIM2 HOOK3 MIF4GD RECK SPG21
Entrez ID		8434	9811
HPRD ID		05567	11083
Ensembl ID		ENSG00000122707	ENSG00000134030
Uniprot IDs		A8K9D8 O95980 Q6P9E2	A0A024R259 O43310
PDB IDs
Enriched GO Terms of Interacting Partners?
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