CMSS1 and S1PR1

Data Source:
BioGRID (two hybrid)

		CMSS1	S1PR1
Description		cms1 ribosomal small subunit homolog	sphingosine-1-phosphate receptor 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytoplasm Endosome Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Intracellular Membrane-bounded Organelle Membrane Raft
	Molecular Function	RNA Binding Protein Binding	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Protein Binding Sphingosine-1-phosphate Receptor Activity Sphingolipid Binding
	Biological Process		Angiogenesis Blood Vessel Maturation Cardiac Muscle Tissue Growth Involved In Heart Morphogenesis Sphingosine-1-phosphate Receptor Signaling Pathway Chemotaxis Cell Adhesion G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Brain Development Cell Migration Cytokine-mediated Signaling Pathway Regulation Of Metabolic Process Transmission Of Nerve Impulse Lamellipodium Assembly Regulation Of Cell Adhesion Neuron Differentiation Positive Regulation Of Cell Migration Regulation Of Bone Mineralization Leukocyte Chemotaxis Actin Cytoskeleton Reorganization Positive Regulation Of GTPase Activity Regulation Of Bone Resorption Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Positive Chemotaxis Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Negative Regulation Of Stress Fiber Assembly Heart Trabecula Morphogenesis T Cell Migration
Pathways			Lysosphingolipid and LPA receptors Interleukin-4 and Interleukin-13 signaling Potential therapeutics for SARS
Drugs			Fingolimod Asfotase alfa Siponimod Ozanimod
Diseases
GWAS		Breast cancer ( 29059683) Facial morphology ( 31763980) Pulse pressure ( 30224653) Refractive error ( 32231278)	Irritable bowel syndrome ( 29673008) Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Multiple sclerosis and C-reactive protein levels (pleiotropy) ( 26920376) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Sensorimotor dexterity ( 31596458) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)
Interacting Genes		3 interacting genes: GYG1 HTR6 S1PR1	9 interacting genes: AKT1 APP CAV1 CMSS1 GNAI1 GNAI3 HTR1A HTR1D PDGFRB
Entrez ID		84319	1901
HPRD ID		11351	03578
Ensembl ID		ENSG00000184220	ENSG00000170989
Uniprot IDs		Q9BQ75	P21453
PDB IDs			3V2W 3V2Y
Enriched GO Terms of Interacting Partners?
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