S1PR1 and CMSS1

Data Source:
BioGRID (two hybrid)

		S1PR1	CMSS1
Description		sphingosine-1-phosphate receptor 1	cms1 ribosomal small subunit homolog
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Intracellular Membrane-bounded Organelle Membrane Raft
	Molecular Function	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Protein Binding Sphingosine-1-phosphate Receptor Activity Sphingolipid Binding	RNA Binding Protein Binding
	Biological Process	Angiogenesis Blood Vessel Maturation Cardiac Muscle Tissue Growth Involved In Heart Morphogenesis Sphingosine-1-phosphate Receptor Signaling Pathway Chemotaxis Cell Adhesion G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Brain Development Cell Migration Cytokine-mediated Signaling Pathway Regulation Of Metabolic Process Transmission Of Nerve Impulse Lamellipodium Assembly Regulation Of Cell Adhesion Neuron Differentiation Positive Regulation Of Cell Migration Regulation Of Bone Mineralization Leukocyte Chemotaxis Actin Cytoskeleton Reorganization Positive Regulation Of GTPase Activity Regulation Of Bone Resorption Endothelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Positive Chemotaxis Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Negative Regulation Of Stress Fiber Assembly Heart Trabecula Morphogenesis T Cell Migration
Pathways		Lysosphingolipid and LPA receptors Interleukin-4 and Interleukin-13 signaling Potential therapeutics for SARS
Drugs		Fingolimod Asfotase alfa Siponimod Ozanimod
Diseases
GWAS		Irritable bowel syndrome ( 29673008) Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Multiple sclerosis and C-reactive protein levels (pleiotropy) ( 26920376) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Sensorimotor dexterity ( 31596458) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)	Breast cancer ( 29059683) Facial morphology ( 31763980) Pulse pressure ( 30224653) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: AKT1 APP CAV1 CMSS1 GNAI1 GNAI3 HTR1A HTR1D PDGFRB	3 interacting genes: GYG1 HTR6 S1PR1
Entrez ID		1901	84319
HPRD ID		03578	11351
Ensembl ID		ENSG00000170989	ENSG00000184220
Uniprot IDs		P21453	Q9BQ75
PDB IDs		3V2W 3V2Y
Enriched GO Terms of Interacting Partners?
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