MIEN1 and HLX

Data Source:
BioGRID (two hybrid)

		MIEN1	HLX
Description		migration and invasion enhancer 1	H2.0 like homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Centriolar Satellite	Chromatin Nucleus
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding
	Biological Process	Apoptotic Process Response To Selenium Ion Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Positive Regulation Of Filopodium Assembly	Liver Development Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Skeletal Muscle Tissue Development Positive Regulation Of Cell Population Proliferation Cell Differentiation Positive Regulation Of T-helper 1 Cell Differentiation Negative Regulation Of T-helper 2 Cell Differentiation Positive Regulation Of Organ Growth Enteric Nervous System Development Embryonic Digestive Tract Morphogenesis
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474 29273806) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic lupus erythematosus ( 28714469)	Apolipoprotein B levels ( 32203549) C-reactive protein levels or total cholesterol levels (pleiotropy) ( 27286809) Cerebrospinal fluid AB1-42 levels ( 26252872) Diverticular disease ( 30177863) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Granulocyte percentage of myeloid white cells ( 27863252) Lung function (FVC) ( 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) PR interval ( 32439900) Triglyceride levels ( 32154731) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for body mass index ( 25673412) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: ARID5A DDIT4L GORASP2 HDAC7 HIVEP1 HLX HMGB2 NLGN3 POU6F2 REL RNF126 TRIP6 VENTX ZBTB32	13 interacting genes: ATXN1L C14orf119 CALCOCO2 CYSRT1 DTX2 FOXH1 LONRF1 MIEN1 PRR20A PRR20B PRR20C PRR20D PRR20E
Entrez ID		84299	3142
HPRD ID		12681	00875
Ensembl ID		ENSG00000141741	ENSG00000136630
Uniprot IDs		J3KTI2 Q9BRT3	Q14774
PDB IDs		2LJK
Enriched GO Terms of Interacting Partners?
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