HLX and DTX2

  • Data Source:
  • BioGRID (two hybrid)

HLX

DTX2

Description H2.0 like homeobox deltex E3 ubiquitin ligase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • C-reactive protein levels or total cholesterol levels (pleiotropy) ( 27286809)
  • Cerebrospinal fluid AB1-42 levels ( 26252872)
  • Diverticular disease ( 30177863)
  • Eosinophil percentage of white cells ( 32888494)
  • FEV1 ( 30804560)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Lung function (FVC) ( 30804560)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Neutrophil count ( 32888494)
  • Obesity-related traits ( 23251661)
  • PR interval ( 32439900)
  • Triglyceride levels ( 32154731)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
  • White blood cell count ( 32888494)
Interacting Genes 13 interacting genes: ATXN1L C14orf119 CALCOCO2 CYSRT1 DTX2 FOXH1 LONRF1 MIEN1 PRR20A PRR20B PRR20C PRR20D PRR20E 131 interacting genes: ABHD11 ABHD16A ALKBH4 ANAPC11 ANTKMT ARID5A ARMC7 ARNT2 BCL2L11 BICRAL BOLA2-SMG1P6 C10orf55 C11orf1 C19orf54 C1orf94 C20orf85 C22orf39 CCDC57 CLPP COA6 COQ8A DAZAP2 DOK3 DTX1 DTX3 ECM1 ECSIT EIF4ENIF1 EIF4G1 EYA2 FAM168A FCRL4 FHL2 FHL5 FOXI1 FTO GLYCTK GOLGA2 HDC HGS HLX HOXA1 HOXB2 HOXD12 HPCA HPCAL1 HPCAL4 HSFY1 HSFY2 IKZF3 KANK2 KLC3 KLHDC7B KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP7-1 KRTAP8-1 LASP1 LNX1 LRP2BP MBD3L1 MDC1 MED19 MSS51 MVP MXRA8 NCALD NCS1 NHLRC4 NIF3L1 NME4 NOTCH1 OIP5 PARP1 PAX5 PLEKHF2 PLEKHG4 PLSCR1 POGZ PPP1R32 PRR32 PRR34 PSMB4 QARS1 RBM11 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 RUSC1 SEC22A SEC23A SEC23B SEPSECS SLC22A18AS SOHLH1 SPAG8 SPG21 STX12 SUMO1 TBX15 TEKT5 TENT2 TMEM42 TRIB3 TRIM35 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBQLN4 USP54 VGLL3 VSNL1 ZNF34 ZNF503 ZNF620 ZNF641 ZNF764 ZNF774 ZNF85
Entrez ID 3142 113878
HPRD ID 00875 16841
Ensembl ID ENSG00000136630 ENSG00000091073
Uniprot IDs Q14774 Q86UW9
PDB IDs 6IR0 6Y22 6Y2X 6Y3J
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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