TRAF7 and RIPK4

Data Source:
BioGRID (affinity chromatography technology, pull down)

		TRAF7	RIPK4
Description		TNF receptor associated factor 7	receptor interacting serine/threonine kinase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleolus Plasma Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Cytoplasm Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Ribosomal Large Subunit Assembly Activation Of MAPKKK Activity Apoptotic Process Notch Signaling Pathway Protein Ubiquitination Positive Regulation Of MAPK Cascade Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Apoptotic Signaling Pathway	Morphogenesis Of An Epithelium Protein Phosphorylation Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Height ( 28552196) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)	Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		12 interacting genes: CDC42 CYLD MAP3K3 OGT RIPK4 TRAF6 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2L3 UBE2L6	10 interacting genes: BIRC2 BIRC3 GPSM3 PRKCB PRKCD RHOA SPAG8 TRAF7 VWC2L XIAP
Entrez ID		84231	54101
HPRD ID		06977	10419
Ensembl ID		ENSG00000131653	ENSG00000183421
Uniprot IDs		B3KQY7 Q6Q0C0	Q96T11 Q9H4D1
PDB IDs
Enriched GO Terms of Interacting Partners?
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