CHD6 and ZFYVE9

Data Source:
HPRD (two hybrid)

		CHD6	ZFYVE9
Description		chromodomain helicase DNA binding protein 6	zinc finger FYVE-type containing 9
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GO Annotations	Cellular Component	Nucleoplasm	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Coregulator Binding DNA Binding DNA Helicase Activity ATP Binding DNA-dependent ATPase Activity	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Chromatin Organization Viral Process DNA Duplex Unwinding Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Diastolic blood pressure ( 27841878) Gastric adenocarcinoma (histologically verified) ( 26098866) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hippocampal atrophy ( 22745009) Low density lipoprotein cholesterol levels ( 32154731) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Refractive astigmatism ( 30306274) Systolic blood pressure ( 27841878) Total cholesterol levels ( 30275531) Triglyceride levels ( 32154731) Verbal declarative memory ( 25648963) Waist circumference ( 31170924)
Interacting Genes		6 interacting genes: ARAF ATXN1L H3-4 NFE2L2 TOLLIP ZFYVE9	38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8
Entrez ID		84181	9372
HPRD ID		13049	04782
Ensembl ID		ENSG00000124177	ENSG00000157077
Uniprot IDs		Q8TD26	O95405
PDB IDs		2EPB	1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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