KAT8 and BAZ2A

Data Source:
BioGRID (enzymatic study, affinity chromatography technology)

		KAT8	BAZ2A
Description		lysine acetyltransferase 8	bromodomain adjacent to zinc finger domain 2A
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Kinetochore Nucleus Nucleoplasm Nuclear Matrix MLL1 Complex MSL Complex	Chromatin Silencing Complex Nucleolus Cytosol Nuclear Speck RDNA Heterochromatin
	Molecular Function	Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Acetyltransferase Activity Enzyme Binding Methylated Histone Binding Histone Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Metal Ion Binding Histone Acetyltransferase Activity (H4-K16 Specific)	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Binding Protein Binding Nuclear Receptor Binding Histone Binding Metal Ion Binding Lysine-acetylated Histone Binding
	Biological Process	Regulation Of Autophagy Histone Acetylation Myeloid Cell Differentiation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	RDNA Heterochromatin Assembly RNA Polymerase I Preinitiation Complex Assembly DNA Methylation Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone Deacetylation
Pathways		HATs acetylate histones	NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 25673413) Family history of Alzheimer's disease ( 30617256) Parkinson's disease ( 28892059) Triglyceride levels ( 32154731)	Mean platelet volume ( 22139419 32888494 27863252) Platelet count ( 22139419 32888494) Platelet distribution width ( 32888494)
Interacting Genes		12 interacting genes: ATM BAZ2A FOXP3 H4C1 KANSL1 KMT2A MSL3 PAF1 PLAU RNF2 TP53 TP53BP1	8 interacting genes: ADRB2 DNMT1 DNMT3B H4C1 HDAC1 KAT8 SMARCA5 TTF1
Entrez ID		84148	11176
HPRD ID		11381	10417
Ensembl ID		ENSG00000103510	ENSG00000076108
Uniprot IDs		Q9H7Z6	F8VU39 Q9UIF9
PDB IDs		2GIV 2PQ8 2Y0M 3QAH 3TOA 3TOB 4DNC 5H43 5J8C 5J8F 5WCI 6BA2 6BA4 6CT2 6OIN 6OIO 6OIP 6OIQ 6OIR 6OWH 6OWI 6PD8 6PD9 6PDA 6PDB 6PDC 6PDD 6PDE 6PDF 6PDG 7CMR	4LZ2 4Q6F 4QBM 4QF2 5AGQ 5MGJ 5MGK 5MGL 5MGM 5OR8 5T8R 6FAP 6FG6 6FGF 6FGG 6FGH 6FGI 6FGL 6FGV 6FGW 6FHU 6FI0 6FKP
Enriched GO Terms of Interacting Partners?
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