ULK1 and ATG9A

Data Source:
BioGRID (pull down, affinity chromatography technology)

		ULK1	ATG9A
Description		unc-51 like autophagy activating kinase 1	autophagy related 9A
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Outer Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axon Guanyl-nucleotide Exchange Factor Complex Phagophore Assembly Site Membrane Recycling Endosome Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane Extrinsic Component Of Autophagosome Membrane Atg1/ULK1 Kinase Complex	Phagophore Assembly Site Autophagosome Membrane Endosome Late Endosome Autophagosome Endoplasmic Reticulum Membrane Trans-Golgi Network Membrane Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Small GTPase Binding Identical Protein Binding Protein-containing Complex Binding GTPase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding
	Biological Process	Protein Phosphorylation Autophagy Signal Transduction Protein Localization Positive Regulation Of Autophagy Macroautophagy Regulation Of Macroautophagy Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Neuron Projection Regeneration Neuron Projection Development Negative Regulation Of Protein-containing Complex Assembly Cellular Response To Nutrient Levels Response To Starvation Protein Autophosphorylation Axon Extension Positive Regulation By Symbiont Of Host Autophagy Positive Regulation Of Autophagosome Assembly	Autophagosome Assembly Autophagy Of Mitochondrion Protein Transport Protein Localization To Phagophore Assembly Site Late Nucleophagy
Pathways		Macroautophagy TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs Receptor Mediated Mitophagy	Macroautophagy
Drugs		Fostamatinib
Diseases
GWAS		Body mass index ( 26426971) Mercury levels ( 26025379)
Interacting Genes		19 interacting genes: ATG9A BECN1 EXOC8 GABARAP GABARAPL1 GABARAPL2 MAPK14 MBP MEFV MUL1 NEDD4L OCLN PPP1CA PRKAA1 SDCBP SMCR8 SYNGAP1 UBC USP20	49 interacting genes: ADAMTSL4 ANKRD10 C11orf1 CERCAM CIB4 CYSRT1 ETHE1 GOPC HDHD3 KLHL20 KPRP KRT31 KRT33B KRT34 KRT35 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP19-1 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP8-1 KRTAP9-2 LONRF1 MAPK6 MEOX1 MEOX2 MGAT5B NBPF19 NDUFB7 NOTCH2NLA OXER1 REL SRC SRCAP TBK1 TCF4 TRIM42 UBE3A ULK1 YPEL3 ZBTB42 ZNF581 ZNF620
Entrez ID		8408	79065
HPRD ID		11933	07979
Ensembl ID		ENSG00000177169	ENSG00000198925
Uniprot IDs		O75385	A0A024R438 Q7Z3C6
PDB IDs		4WNO 4WNP 5CI7 6HYO 6MNH 6QAS	6WQZ 6WR4 7JLO 7JLP 7JLQ
Enriched GO Terms of Interacting Partners?
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