L3MBTL2 and PAICS

  • Data Source:
  • BioGRID (two hybrid)

L3MBTL2

PAICS

Description L3MBTL histone methyl-lysine binding protein 2 phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Crohn's disease ( 26192919)
  • Depression ( 29700475)
  • General risk tolerance (MTAG) ( 30643258)
  • Inflammatory bowel disease ( 26192919)
  • Lamb consumption ( 32066663)
  • Major depressive disorder ( 27479909)
  • Neuroticism ( 29255261 27918536)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 49 interacting genes: AMOTL2 BEND7 BHLHB9 BIVM CARD9 CCDC106 CCDC33 CEP76 EFHC2 EIF4ENIF1 FAM217B GAS8 GKAP1 GOLGA2 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829 18 interacting genes: CDC37 CEP76 CHD3 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PIAS2 PILRA PRKAG1 RAD54L2 RNF4 SMARCD1 TERF1 UBE2I ZMYM2
Entrez ID 83746 10606
HPRD ID 13954 01401
Ensembl ID ENSG00000100395 ENSG00000128050
Uniprot IDs A0A0S2Z5X6 Q969R5 P22234
PDB IDs 2W0T 3CEY 3F70 2H31 6YB8 6YB9
Enriched GO Terms of Interacting Partners?
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