INHBE and PIP4K2C

Data Source:
BioGRID (two hybrid, two hybrid)

		INHBE	PIP4K2C
Description		inhibin subunit beta E	phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Collagen-containing Extracellular Matrix	Nucleoplasm Autophagosome Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Organelle Extracellular Exosome
	Molecular Function	Cytokine Activity Hormone Activity Growth Factor Activity	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Identical Protein Binding
	Biological Process	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction	Phosphatidylinositol Biosynthetic Process Regulation Of Autophagy Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Phosphorylation Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly
Pathways		Glycoprotein hormones	Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus
Drugs			Fostamatinib
Diseases
GWAS		HDL cholesterol ( 30275531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Urate levels ( 23263486)	Rheumatoid arthritis ( 18794853)
Interacting Genes		1 interacting genes: FST	4 interacting genes: APP BTK FBXO25 PJA1
Entrez ID		83729	79837
HPRD ID		11047	15138
Ensembl ID		ENSG00000139269	ENSG00000166908
Uniprot IDs		P58166	B3KQV3 Q8TBX8
PDB IDs			2GK9
Enriched GO Terms of Interacting Partners?
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