PIP4K2C

Description		phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
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GO Annotations	Cellular Component	Nucleoplasm Autophagosome Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Organelle Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Identical Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Regulation Of Autophagy Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Phosphorylation Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly
Pathways		Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus
Drugs		Fostamatinib
Diseases
GWAS		Rheumatoid arthritis ( 18794853)
Novel Interacting Genes		1 novel interacting genes: INHBE
Interacting Genes		4 interacting genes: APP BTK FBXO25 PJA1
Entrez ID		79837
HPRD ID		15138
Ensembl ID		ENSG00000166908
Uniprot IDs		B3KQV3 Q8TBX8
PDB IDs		2GK9
Enriched GO Terms of Interacting Partners?
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