INHBE and FST

Data Source:
HPRD (in vitro)

		INHBE	FST
Description		inhibin subunit beta E	follistatin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Space Nucleus Cytoplasm
	Molecular Function	Cytokine Activity Hormone Activity Growth Factor Activity	Protein Binding Activin Receptor Antagonist Activity Heparan Sulfate Proteoglycan Binding Activin Binding
	Biological Process	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Hematopoietic Progenitor Cell Differentiation Multicellular Organism Development Gamete Generation Pattern Specification Process Female Gonad Development Cell Differentiation BMP Signaling Pathway Regulation Of BMP Signaling Pathway Hair Follicle Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Odontogenesis Of Dentin-containing Tooth Keratinocyte Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of Hair Follicle Development
Pathways		Glycoprotein hormones	Antagonism of Activin by Follistatin
Drugs			D-Myo-Inositol-Hexasulphate
Diseases
GWAS		HDL cholesterol ( 30275531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Urate levels ( 23263486)	Acne (severe) ( 24927181 30542056) Alzheimer's disease (late onset) ( 30820047) Central corneal thickness ( 32528159) Estimated glomerular filtration rate ( 31152163) HDL cholesterol levels ( 32203549) Height ( 31562340) High-grade serous ovarian cancer ( 31469419) Intraocular pressure ( 29617998 29235454) Midgestational circulating levels of PCBs ( 28235828) Optic disc size ( 31809533) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: FST	14 interacting genes: BEX2 BMP5 C8orf33 CATSPER1 CREB5 FN1 HOXA1 INHA INHBA INHBE MEST TK1 TXN ZNF587
Entrez ID		83729	10468
HPRD ID		11047	00641
Ensembl ID		ENSG00000139269	ENSG00000134363
Uniprot IDs		P58166	A0A024QZU6 P19883
PDB IDs			2B0U 2P6A 3HH2 5JHW
Enriched GO Terms of Interacting Partners?
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