DGCR6 and ESS2

Data Source:
BioGRID (two hybrid)

		DGCR6	ESS2
Description		DiGeorge syndrome critical region gene 6	ess-2 splicing factor homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Extracellular Matrix	Nucleus Catalytic Step 2 Spliceosome
	Molecular Function	Molecular_function Protein Binding	Molecular_function Protein Binding
	Biological Process	Cell Adhesion Animal Organ Morphogenesis	MRNA Splicing, Via Spliceosome Nervous System Development
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Metabolite levels ( 23823483) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)
Interacting Genes		66 interacting genes: ADAMTSL4 AGTRAP AKAP8L APP ARNT2 C1orf94 C3orf62 CBLL1 CBY2 CCDC33 CEP126 CTBP1 DEUP1 DLGAP2 DLX2 DNPEP DOCK8 EFEMP2 EFHC2 ENKD1 ESS2 FBF1 FH GOLGA2 GSE1 HGS HOMEZ IHO1 IKZF3 INIP KLHL12 KRTAP12-2 LZTS2 MBIP MEIS2 MEOX2 MIA2 MID2 MIPOL1 NAB2 NECAB2 NOTCH2NLA NQO2 NUP54 NUP62 PDLIM7 PRDM14 RABGEF1 REL RFX6 RIMBP3 SPRY2 SS18L1 TCF12 TCF4 TFIP11 TLE5 TRAF1 TRAF2 TRIM27 TUBGCP4 VCP ZBED1 ZC4H2 ZNF398 ZNF446	18 interacting genes: ARMC7 CCDC57 CDK5RAP3 CRP DGCR6 DHX16 EXOC8 FRA10AC1 LYST OIP5 PFDN1 QARS1 RACK1 RBM4 SMARCD1 TTC14 VIM WNK2
Entrez ID		8214	8220
HPRD ID		03177	03452
Ensembl ID		ENSG00000183628	ENSG00000100056
Uniprot IDs		Q14129 X5D7D2	F8WEF8 Q96DF8
PDB IDs
Enriched GO Terms of Interacting Partners?
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