CLPP and CLPX

Data Source:
HPRD (in vitro)

		CLPP	CLPX
Description		caseinolytic mitochondrial matrix peptidase proteolytic subunit	caseinolytic mitochondrial matrix peptidase chaperone subunit X
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Endopeptidase Clp Complex	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol Endopeptidase Clp Complex Mitochondrial Endopeptidase Clp Complex Mitochondrial Nucleoid
	Molecular Function	Endopeptidase Activity ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Identical Protein Binding ATPase Binding	ATP-dependent Peptidase Activity Protein Binding ATP Binding Zinc Ion Binding Peptidase Activator Activity ATPase Activity Protein Dimerization Activity Unfolded Protein Binding
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Membrane Protein Proteolysis Proteolysis Involved In Cellular Protein Catabolic Process	Protein Folding Proteolysis Positive Regulation Of Peptidase Activity Protein Catabolic Process ATP Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process
Pathways
Drugs		N-Formylmethionine
Diseases
GWAS
Interacting Genes		16 interacting genes: ABI2 C14orf119 CLPX DTX2 EFEMP1 EFEMP2 GRN KRTAP10-1 NUTF2 P4HA3 PLSCR4 PPP2CA PSMB1 RBPMS TNPO3 TRIM54	2 interacting genes: CLPP FBXL17
Entrez ID		8192	10845
HPRD ID		03074	07478
Ensembl ID		ENSG00000125656	ENSG00000166855
Uniprot IDs		Q16740	A0A024R5X7 O76031
PDB IDs		1TG6 6BBA 6DL7 6H23
Enriched GO Terms of Interacting Partners?
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