BHLHB9 and LEO1

Data Source:
BioGRID (two hybrid)

		BHLHB9	LEO1
Description		basic helix-loop-helix family member b9	LEO1 homolog, Paf1/RNA polymerase II complex component
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome	Fibrillar Center Nucleus Nucleoplasm Centrosome Cdc73/Paf1 Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding RNA Polymerase II C-terminal Domain Phosphoserine Binding
	Biological Process	Learning Or Memory Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neurogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Dendritic Spine Morphogenesis	Endodermal Cell Fate Commitment Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Polyadenylation Histone Monoubiquitination Wnt Signaling Pathway Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Negative Regulation Of Myeloid Cell Differentiation Beta-catenin-TCF Complex Assembly
Pathways			Formation of RNA Pol II elongation complex Formation of the beta-catenin:TCF transactivating complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Interacting Genes		59 interacting genes: ANKRD11 APP AQP1 BEX2 C2CD6 CCDC120 CDC23 CDC37 CDCA7L CT55 DDX6 EAF1 EIF3B ENKD1 FAM124B FAM161A FAM214B FAM90A1 GAS8 GEM GPANK1 HOXA1 INO80B IPO5 IQUB KLHL38 L3MBTL2 LEO1 LMO1 LONRF1 MFAP1 MISP MPP1 MYO15B NRIP1 OTX1 PALS1 PHF1 PNMA5 POLR1C PPP2R5E PRKAB2 PRPF31 RCOR3 SCNM1 SH3KBP1 SMARCD1 SPANXN2 TASOR2 TCEA2 TEPSIN THOC1 TLK1 TOP3B TSGA10IP TXN2 USP2 USP20 ZNF417	9 interacting genes: BHLHB9 CSNK2A1 CTNNB1 ERCC6 H1-2 PAF1 POLR2A TCEA1 TCEA3
Entrez ID		80823	123169
HPRD ID		10028	11231
Ensembl ID		ENSG00000198908	ENSG00000166477
Uniprot IDs		Q6PI77	Q8WVC0
PDB IDs			4M6T 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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