FOSL1 and WFDC1

Data Source:
BioGRID (two hybrid)

		FOSL1	WFDC1
Description		FOS like 1, AP-1 transcription factor subunit	WAP four-disulfide core domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Presynaptic Membrane Neuron Projection	Extracellular Space
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Molecular_function Serine-type Endopeptidase Inhibitor Activity
	Biological Process	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Chemotaxis Cellular Defense Response Vitellogenesis Female Pregnancy Learning Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Response To Mechanical Stimulus Response To Virus Response To Gravity Cellular Response To Extracellular Stimulus Response To Progesterone Response To Cytokine Response To Drug Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of DNA-binding Transcription Factor Activity Response To Corticosterone Response To CAMP Placenta Blood Vessel Development Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Initiation	Regulation Of Cell Growth Negative Regulation Of Endopeptidase Activity Negative Regulation Of Cell Growth Response To Estradiol Response To Drug Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Inflammatory Response Negative Regulation Of Wound Healing
Pathways		NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 23128233) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252)	Blood protein levels ( 30072576) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Systolic blood pressure (alcohol consumption interaction) ( 24376456) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		30 interacting genes: ATF2 ATF3 ATF4 ATXN1 BATF3 CALCOCO1 CCDC120 CEBPA CEBPE CEBPG CREB5 DDIT3 DNMT3L EP300 ERCC6 GCC1 JUN JUNB KIFC3 KPNA1 LDOC1 MAF MAFB NME7 PARVG PIN1 TAB2 TRIM24 USF1 WFDC1	5 interacting genes: EZR FOSL1 RAB40B XRCC2 ZNF677
Entrez ID		8061	58189
HPRD ID		00643	05614
Ensembl ID		ENSG00000175592	ENSG00000103175
Uniprot IDs		A0A0S2Z595 E9PKL5 E9PPX2 P15407	Q9HC57
PDB IDs
Enriched GO Terms of Interacting Partners?
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