GKAP1 and SOX18

Data Source:
BioGRID (two hybrid)

		GKAP1	SOX18
Description		G kinase anchoring protein 1	SRY-box transcription factor 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Binding Identical Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Signal Transduction Positive Regulation Of Insulin Receptor Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Vasculogenesis In Utero Embryonic Development Hair Follicle Development Vasculature Development Lymphangiogenesis Heart Looping Outflow Tract Morphogenesis Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Hair Cycle Process Cell Differentiation Embryonic Heart Tube Development Blood Vessel Endothelial Cell Migration Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cell Maturation Stem Cell Fate Specification Endocardium Formation Lymphatic Endothelial Cell Differentiation Endocardial Cell Differentiation Establishment Of Endothelial Barrier Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases			Lymphedemas, including: Lymphedema, hereditary I; Lymphedema-distichiasis syndrome (LD); Hypotrichosis-lymphedema-telangiectasia syndrome (HLTS)
GWAS		Chronotype ( 30696823) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Triglyceride levels ( 32154731)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Refractive error ( 32231278)
Interacting Genes		22 interacting genes: AP3B1 C1orf35 DHFR FAM124B FXR2 HDDC3 HGS HSD11B1 KANK2 KAT5 L3MBTL2 MFAP1 NDN PHOSPHO2 PRKG1 RCOR3 SDCBP SH3BP4 SOX18 UBQLN1 UBQLN4 ZCCHC10	5 interacting genes: AURKA GKAP1 HMGB1 MECP2 MEF2C
Entrez ID		80318	54345
HPRD ID		17042	07208
Ensembl ID		ENSG00000165113	ENSG00000203883
Uniprot IDs		Q5VSY0	P35713
PDB IDs
Enriched GO Terms of Interacting Partners?
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